DNA analysis: identify your personal health risk factors
Learn about your unique genetic risk factors through our DNA analysis and how you can take proactive steps to prevent chronic diseases effectively.
Your genetics account for about 20% of your health
Your health today and in the future is shaped by many factors, but the foundation lies in your genetic code—your DNA—which you inherit at birth. Your DNA accounts for roughly 20% of your health and lifespan. Understanding your genetic risks empowers you to take control of your well-being. The encouraging news? At least 80% of your health can be influenced by the choices you make.
Our DNA risk tests provide a detailed picture of your unique genetic code by analyzing specific genetic variations, called SNPs (Single Nucleotide Polymorphisms), associated with an increased likelihood of various diseases. This analysis reveals the hidden risks for chronic illnesses in your DNA, potential treatment options, and actionable lifestyle changes to help you maintain optimal health for as long as possible.
Our DNA Risk Analysis takes a preventative approach, providing early insights into your genetic risk factors along with practical guidance on reducing the likelihood of chronic diseases.
We analyze specific genetic variations that provide valuable insights into key bodily processes, including fat metabolism, methylation, detoxification, inflammation, oxidative stress, bone health, insulin resistance, vitamin metabolism, and responses to certain foods.
Longevity Check-up: DNA risk analysis
The AYUN Longevity Check-up takes approximately 5 hours. The Complete and Extended Check-up include the DNA risk analysis, an important step to understand your genetic code. This step is completed during the blood draw and takes 20 minutes.
20 min
Uncover the benefits of our check-upsWhat DNA risks do we analyze?
Fat Metabolism
Your heart health, vascular function, and even memory are influenced by a combination of environmental factors, nutrition, and genetics. Specific genetic variations also affect LDL and HDL cholesterol levels. By understanding your genetic profile related to fat metabolism, we can address potential risks more effectively.
Methylation
B vitamins, such as folate (vitamin B9), vitamin B6, and B12, are essential for cell renewal, growth, and numerous metabolic processes. They support DNA formation and repair, break down vessel-damaging metabolic products like homocysteine, and significantly impact mental health. These vitamins must often be converted into their active forms (like methylfolate) to participate in methylation reactions that regulate important enzymes and metabolic processes. Genetic variations, such as mutations in the MTHFR gene, can affect these processes, leading to suboptimal metabolic function. Understanding these genetic risks allows us to implement targeted measures to support and optimize these processes long-term.
Detoxification
Detoxification occurs in two phases. In Phase 1, enzymes chemically modify substances like environmental toxins, medications, or metabolic byproducts, often creating reactive intermediates that must be processed quickly. Phase 2, governed by the GST enzyme group (Glutathione-S-Transferases), neutralizes these harmful substances by binding them to glutathione, making them water-soluble and easier to excrete via urine or bile. Genetic changes can disrupt or slow this process, making it essential to identify these risks and support detoxification through targeted interventions.
Inflammation
Acute inflammation is a normal immune response essential for healing processes. Specific genes regulate the release of inflammatory factors, but if these genes fail to “switch off” properly, acute inflammation can transition into chronic, low-grade inflammation. Chronic inflammation is linked to numerous conditions, including obesity, cardiovascular disease, arthritis, and diabetes. By identifying genetic risks for persistent inflammation, we can implement strategies to prevent chronic diseases.
Oxidative Stress
Free radicals can damage proteins, DNA, and cell membranes. Antioxidants neutralize these free radicals, preventing further harm. Genetically determined antioxidant enzymes play an important role in fighting free radicals. When genetic variations reduce the activity or production of these enzymes, targeted measures can be taken to prevent the damages of oxidative stress.
Bone Health
Bone health and density are crucial for maintaining mobility and longevity. Reduced bone density can increase the risk of fractures and limit mobility long-term. When there's an elevated genetic risk for compromised bone health, targeted interventions can help reduce the risk of developing osteoporosis.
Insulin Resistance
Insulin is a hormone that facilitates the uptake of glucose into cells. Increased insulin resistance, where the body responds less effectively to insulin, is a key factor in the development of conditions such as obesity, type 2 diabetes, hypertension, heart disease, and lipid metabolism disorders. Identifying genetic risks for insulin resistance allows for the implementation of preventive measures to reduce the likelihood of these metabolic issues.
Vitamin Metabolism
Vitamin needs vary based on factors such as age, gender, pre-existing conditions, and genetics. We analyze genes that affect your need for vitamins A, D, C, and B12 to provide personalized recommendations for optimal vitamin intake.
Food Sensitivities
Different nutrients and foods can affect individuals in unique ways. Genetic testing helps us understand your personal responses to dietary components such as lactose, polyunsaturated fatty acids, caffeine, salt, iron, and alcohol. Genetic factors can also affect gut health, contributing to conditions like lactose intolerance, gluten sensitivity, or irritable bowel syndrome. This knowledge enables you to tailor your diet to support your health and well-being effectively.
How is the DNA check performed?
Choose the Longevity Check-up
that suits you
Essential
Our Essential Longevity Check-up evaluates your blood values, body composition, and physical performance, offering deep insights into your personal health and fitness.
Complete
In addition to blood values, body composition, and performance, our Complete Longevity Check-up assesses your DNA risks and blood sugar levels. This helps us identify your individual genetic risk factors and determine your optimal nutrition strategy.
Extended
Our most comprehensive package, the Extended Longevity Check-up includes all AYUN tests, such as determining your biological age and heart rate variability. This allows us to uncover your unique stress triggers and relaxation factors.
Frequently Asked Questions
Longevity Check-ups
At what age do you recommend the Longevity Check-up?
In general, a Longevity Check-up is recommended for anyone over the age of 25. The earlier you know what your individual health risks are, the longer you can benefit from small adjustments. But it is never too late to take charge of your health and optimize it in a targeted way, i.e. even at an advanced age, there is still a lot of potential for optimization.
How long does a Longevity Check-up take?
A Longevity Check-up lasts about 4-5 hours depending on the package chosen. It starts with a 30-45 minute anamnesis interview with one of our doctors, followed by an ECG, blood draw, and Dexa scan. You'll then have a brief snack break before completing the 1.5 hour session with our sports scientist. Afterwards, wearables such as the HRV monitor and the CGM are attached and set up.
What do I need to bring for my Longevity Check-up?
You should arrive fasted (empty stomach, water allowed) and bring your sports clothes for the sports and endurance test. Showers and towels are available.
How long does it take to get the results of my check-up?
This depends on the Longevity Check-up you have chosen. The time between the test and receiving your results depends on external laboratories and the time our team of doctors, nutritionists and sports scientists need to evaluate your results. The indicative time is as follows:
- Essential Longevity Check-up: 1-2 weeks
- Complete Longevity Check-up: 4-5 weeks (due to the DNA risk analysis)
- Extended Longevity Check-up: 4-5 weeks (due to the DNA risk analysis and DNA aging clock)
Do I have to come to your clinic to discuss my results?
The discussion of the results usually takes place at our clinic. If you prefer, the conversation can also take place via video conference.
The same applies to the nutrition counseling, which can take place either on-site or via video conference.
What makes you different from other check-ups?
Our focus is not just on identifying diseases at an early stage, but rather on understanding individual predispositions and determining what each individual needs to stay healthy in the long term. We don't look at individual values, but combine all the results into a holistic picture. We collect scientifically validated parameters for Longevity and combine them into a personalized, preventative Longevity Report.
Who performs the Longevity Check-ups?
We are a medical institution, so all check-ups are performed by trained and medically educated personnel. We employ doctors, medical assistants and sports scientists in our clinic.
What is the difference between the Essential Longevity Check-up and the Complete Longevity Check-up?
All our check-ups focus on longevity. The Essential Longevity Check-up contains what we consider to be absolutely necessary for a Longevity Check-up and is suitable for people who want to get a first impression or as a follow-up check-up if you already know your genetic risks.
The Complete Longevity Check-up includes, in addition to further blood values, such as homocysteine, the DNA risk analysis, which we recommend to do once in a lifetime. The DNA risk analysis helps us to make even more targeted recommendations. We only test for those changes for which we know how we can influence them well and specifically.
In addition, continuous blood sugar monitoring for 10 days is included, with accompanying nutritional counseling for evaluation and interpretation. The blood sugar response to different foods can vary greatly from person to person, which is why these measurements can be used to provide even more targeted nutritional recommendations.
What is the difference between the Complete and Extended Longevity Check-up?
The first difference is the number of laboratory values analyzed. The Complete Longevity Check-up includes 64 laboratory values and the Extended Longevity Check-up 69 laboratory values. In addition, the Extended Longevity Check-up also includes a stress measurement (both during the day and at night) and a DNA aging clock to determine your biological age.
How are the findings evaluated?
Our team of doctors, nutritionists and sports scientists analyze the findings holistically, prioritize and make appropriate recommendations.
We compare the results with comparative values from your age and gender group. Our goal is for our customers to perform significantly better than the average, because the average person develops chronic diseases over the course of their life that significantly affect their quality of life.
Others
Everyone knows what is healthy: exercise, nutrition and sleep. What else do you offer?
That's right, healthy eating, regular exercise and enough sleep are the cornerstones of longevity. General recommendations are certainly suitable for the masses, but when it comes to looking at the individual, many individualized recommendations can be made depending on the individual disposition constellation. Our goal is to achieve the greatest possible health effect for the individual with the least possible effort. To do that, much more precise recommendations are useful and possible.
Can I bring my child with me?
Our services are only available to persons of legal age. However, you are welcome to bring a child with you as a companion. No childcare service is available.
Do you also offer payment by installments?
We're working on standardizing installment payment options in our checkout process. In the meantime, if you'd like to use an installment plan, feel free to give us a call, and we'll find a solution together.
